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paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The “gut microbiota-ferroptosis

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Food Chem.,MorgaviD

paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

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paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

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paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

Immunohistochemical staining of GSTA1 was conducted to evaluate the expression of GSTA1 in mouse liver using the fixed liver samples and liver tissue chip of MASLD patients (#DN035Lv01 bioaitech, Xian, China), and then was analyzed by the H-Score indicator

paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

Vesicular transport assays further demonstrated that ABCC1 actively transports the Fe-GSH complex, formed under physiological glutathione levels, indicating its role in regulating the labile iron pool and reducing intracellular iron toxicity

paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

However, the specific subcellular compartment in which the GCH1-BH4 system works remains to be determined

paraxanthine elevates catalase glutathione increases The changing faces of glutathione, a cellular protagonist., Volume I Frontiers | The gut microbiota-ferroptosis

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