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ii) Utilizing the steric hindrance conferred by dimerization reduces protease access to the active site and significantly improving stability against proteases 49,50

doi: 10.1038/s41598-018-24257-7

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taken on an empty stomach or 30 minutes before meals to maximize contact with gastric and intestinal mucosa Duration 8 to 12 weeks per cycle, or longer under physician supervision for chronic GI conditions

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Glutathione S-transferases: Structure and mechanism of an archetypical detoxication enzyme