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Letybos approval is supported by data from three Phase III trials comprising more than 1,200 participants and showing that the drug elicited significant treatment success, defined as no or mild glabellar lines and an improvement of at least two points on the Glabellar Line Scale versus baseline, according to its label

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Malhotra R, Craven T, Ambrosius WT, Killeen AA, Haley WE, Cheung AK, et al

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These spots often called age spots or hyperpigmentation happen when UV exposure overstimulates melanin production

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J Biol Chem (2000) 275:1711421.10.1074/jbc.M908959199 138 StorzPDopplerHTokerA

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Novel pharmacotherapies are urgently needed to address the complex neurobiological changes that occur both during and after MUD

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