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Genetic silencing or isoform-specific inhibitor of HDAC is required in the future to clarify the exact role of each HDAC isotype following epileptic condition

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Nat Struct Mol Biol 14(5):420426

Since in this study IGF-I is correlated with a lower RBC deformability, measured with viscometry at high shear rate [155], this observation raises the possibility of a direct effect of IGF-I on RBC deformability via the binding of this hormone on its receptors on the red cell membrane