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In addition, ERAP1 downregulation could influence trimming of Class I-bound precursor peptides, which in turn could affect the peptide repertoire and the conformational stability of Class I: peptide complexes 11

Animals were sacrificed at 0.5, 1, 4, 24 hours and 1, 2, and 3 weeks after TNBS+ethanol administration and colonic mucosa was obtained for evaluation of damage, GSH content, total RNA isolation and protein content

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Detoxifies the Liver Glutathione is most commonly found in our livers, waiting for any toxins to flow through so it can attach to them and help get them out of the body
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Overexpression of miR-155 decreases C/EBP levels, thereby reducing the accumulation of fatty acids within lipid droplets in the liver [322]
