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For polymer of hydrocarbon, oxidation must precede biodegradation

Sloan Kettering Institute

Our study also found that NRF2, GPX4 and SOD1 expression levels were higher in the neoadjuvant chemotherapy-resistant group compared to the sensitive group, further supporting our hypothesis and demonstrating the adverse effects of GSH on chemotherapy in breast cancer patients

3.2.3.2 The amelioration of joint destruction via oxidative factors Oxidative stress plays a central role in the onset and persistent development of RA, serving as a crucial mechanism leading to sustained inflammation and joint damage (124)

Alongside these deficits, we investigate the compensatory roles of GSH-independent rescue networks, namely ferroptosis suppressor protein 1 and mitochondrial dihydroorotate dehydrogenase

doi: 10.1002/jcb.23431 209 OliveiraALBMonteiroVVSNavegantes-LimaKCReisJFGomesRSRodriguesDVSet al