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The Keap1Nrf2ARE pathway serves as an antioxidant pathway

To measure ADCC, we first made a REW version engineered for low content of N297-linked fucose which considerably increased binding to FcRIIIa (Fig

Alam, J., Kim, Y

Genomic alterations (e.g., activation of KRAS, PI3K mutation, MET amplification) and tumor genotype have a strong impact on whether EGFR inhibition by phytochemicals suppresses tumor growth and in certain genetic backgrounds EGFR inhibition is circumvented and no cytotoxic effect is observed despite biochemical target modulation [344]

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doi: 10.3390/molecules26051417