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Khalaf K, Tornese P, Cocco A, Albanese A

Peroxidases, including glutathione peroxidase 4 (GPX4), metabolize hydroperoxy-phospholipids to hydroxy derivatives to prevent ferroptotic death, but consume reduced glutathione (GSH)

Findings on serial MRI in a childhood case of L2-hydroxyglutaric aciduria

A DSEA pathways analyses suggests these drugs upregulate secretion and activate pathways related to cell-cell, cell-matrix interactions, neuronal survival and differentiation suggesting possible new mechanistic targets for designing novel radioprotective drugs

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (RS-2026-25469433) (to W.S.B.)