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Prioritized genes at novel loci included genes involved in transcription ( CASZ1 , PPARGC1A , ZNF641 , MED4-AS1 , ZFHX3 , ZGPAT , MAFF ), cellular signaling and differentiation ( ACVR2B , DCDC2 , GRB10 , THADA , TRIB1 , PTPN3 ), metabolism ( L2HGDH , XYLB ), solute carrier genes ( SLC25A43 , TPCN2 , KCNMA1 , MFSD6 ), and genes related to AB antigen blood types ( ABO, FUT2 )

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GHK-Cu levels in the body decline significantly with age