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Additionally, melanocortins such as -melanocyte-stimulating hormone (-MSH), produced by both keratinocytes and melanocytes, activate the melanocortin-1 receptor (MC1R) on melanocytes, further enhancing their antioxidant capacity

In bacteriostatic water at 2-8C, most peptides remain stable for four to six weeks

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These systems also allow for sustained release, maintaining steady peptide concentrations in the bloodstream and enhancing efficacy [68]
These help to defend the skin from environmental stressors

At least half of sun-related skin damage is due to free radical formation, and theres mounting evidence that topical antioxidants like glutathione, alpha-lipoic acid and vitamin C can mitigate some of this damage and reduce signs of skin aging