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PTX, as a microtubule inhibitor, interfered with microtubule dynamics by stabilizing microtubule polymerization, resulting in abnormal chromosome condensation, and finally formed mitotic catastrophe [199]

yellow), KP (purple), and KPA (red) tumours (Supplementary Fig

When these axons are disrupted, it affects communication between different parts of the brain, impairing its normal functioning

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Mayo Clin Proc 71(4):384389 Hausmann ON (2003) Post-traumatic inflammation following spinal cord injury