how does l-carnitine treat valproate induced hyperammonemia Reversible weakness and encephalopathy while on long-term treatment due to carnitine deficiency Valproate-induced hyperammonemic encephalopathy treated by

Exp Neurol 161:115126 Vereczki V, Martin E, Rosenthal RE, Hof PR, Hoffman GE, Fiskum G (2006) Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death

Hepatic steatosis is further aggravated by impaired fatty acid oxidation in an ethanol-impaired liver (79)

The amount naturally present is quickly depleted

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Intravenous L-carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in hemodialysis patients

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