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For other primary fetal cortical neurons and stem cells, a significant reduction of cell viability was only observed in older cultures [71,74], as well as in HCN-1A and IMR-32 cell lines for which a significant loss of viability was observed after a 24 h incubation [68,70]
However, excessive ROS production can disrupt cellular homeostasis, resulting in severe oxidative damage (28)
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Tumor cells play a pivotal role in undermining immune function
on the other, it can intensify oxidative stress by altering metabolic pathways (121)
Akunna, O.A
