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There are several cellular systems in place to ensure the maintenance of a healthy population of functional mitochondria

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Gastrointestinal adverse events were the most frequently reported, but were predominantly mild to moderate

It is important to check folate status alongside B12, but folate supplementation should not be started before excluding B12 deficiency, as this may precipitate neurological complications

10.1016/j.mam.2013.01.002 66 MoulouelB.HouamelD.DelabyC.TchernitchkoD.VaulontS.LetteronP.et al (2013)