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Activation of NF-B with induction of neuronal apoptosis was established in PD patients compared to the controls (Hunot et al

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Studies with duplicated data, non-RCT design, animal studies, studies that assess the effects of green tea supplementation and other interventions, and those with insufficient data for the outcomes of interest or did not meet inclusion criteria of our meta-analysis were excluded

Janos Zempleni, DonaldM Mock, Biotin biochemistry and human requirements, The Journal of Nutritional Biochemistry, Volume 10, Issue 3, 1999, Pages 128-138, ISSN 0955-2863, Said HM

Kestin AS, Valeri CR, Khuri SF, Loscalzo J, Ellis PA, MacGregor H, et al

Evidence increasingly supports an elevated risk associated with persistent, intensive NSW, particularly when initiated early in life or combined with genetic susceptibility