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Mice were first acclimatized to the metabolic home cages for 24 h before data were collected for analysis

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Potential interventions to mitigate immunosenescence, including reshaping immune organs, targeting different immune cells or signaling pathways, and nutritional and lifestyle interventions, are summarized

[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Dou H, Kotini A, Liu W, Fidler T, Endo-Umeda K, Sun X, et al

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In addition, to its role in redox reactions of the oxidative phosphorylation pathway, copper is essential for the function of numerous metalloenzymes referred to as cuproenzymes