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Glycolysis versus OXPHOS CSCs often demonstrate a remarkable ability to toggle between glycolysis and OXPHOS, flexibility that supports their survival in diverse and frequently hostile tumor niches

This limitation is shared by most unmodified peptides and is why pharmaceutical peptide drugs require extensive chemical modification or alternative delivery routes

doi: 10.1530/JOE-17-0002

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Psychopharmacology (Berl.) 2013;225(2):473482

Alternative treatments covered by insurance should be discussed to ensure financial considerations do not unduly influence treatment decisions when more established alternatives exist