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Reactive oxygen species mediate virus-induced STAT activation: role of tyrosine phosphatases

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ApoE4 is more efficient than E3 in brain access by herpes simplex virus type 1

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doi: 10.1038/nature03286 8 BlankenshipR

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Epithelial cells express NOX1 and DUOX2, which produce ROS into the extracellular space or gut lumen (121123), whereas phagocytes (neutrophils, eosinophils, macrophages) express NOX2 (phagocyte oxidase) that produces superoxide inside phagosomes or can leak it outside (124, 125)

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Body Composition The scale often doesn't reflect the dramatic changes happening

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10.1164/rccm.202105-1268OC

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