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After incubation, the cultures were filtered and the enzyme activity was assessed

Of note, a survey revealed that over 86% of patients using glutathione nasal spray rated this route of administration as convenient and easy to use, supporting good compliance [212]

In the MPTP model of PD, treatment with OLT1177 can prevent the loss of motor function by inhibiting NLRP3, reducing -synuclein levels, modulating proinflammatory markers in the substantia nigra-striatum region, and protecting dopaminergic neurons from degeneration, thereby improving PD symptoms [167]