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PMID: 18546825

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Glycine transporter-I inhibitors: a new class of antidepressant

doi: 10.1016/S0039-6028(02)01375-4 27 NawazT.ShafiM.KhaliqA

4 Professor, Centre for Cardiovascular Science, Queen's Medical Research Institute, Edinburgh, Scotland Background: Deranged glucose metabolism has deleterious cardiovascular and renal consequencies, predicted by disrupted circadian variation in blood pressure (BP)

Amgen will now be required to run an additional confirmatory study to be completed no later than February 2028, the company stated in a press release announcing the Complete Response Letter