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WB results demonstrated that the increased expression of NEDD4 after COM treatment was restored after the knockdown of UBE2m in HK-2 cells (Fig

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Prebiotics enhance probiotic proliferation and restore gut microbiota balance, which may alleviate gastrointestinal symptoms in ASD patients (Palmer et al., 2025)

Therefore, further investigations are needed to assess potential vascular effects of hyperhomocysteinemia-associated changes in the SAM to SAH ratio, which regulates SAM-dependent methyltransferases and hence, methylation reactions

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