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These data represent evidence of the involvement of excessive levels of NO in the pathogenesis of ASD

Intense Pulsed Light (IPL) IPL uses broad-spectrum light to address diffuse pigmentation and redness

Cervicovaginal microbiome, high-risk HPV infection and cervical cancer: mechanisms and therapeutic potential

Excess ROS then activates the NLRP3 inflammasome in microglia, promoting maturation and release of IL-1 ( 4.3 GSH metabolism: a central hub in mid-late SAE The hippocampus, with its high metabolic demands and low antioxidant capacity, is uniquely vulnerable to septic injury ( A Stat1-Gpx3 hub was identified, where TNF-/IL-1-induced Stat1 activation suppresses Nrf2 (confirmed by reduced hippocampal Nrf2)

Increased BBB permeability allows neurotoxic substances and bioactive molecules, such as glutamate, norepinephrine, epinephrine and glycine, to infiltrate the brain, disrupting neurotransmitter balance