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Furthermore, this approach establishes a theoretical foundation for the clinical implementation of combination tumor therapy

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Fibroblasts derived from these CIPO-LIG3 patients exhibit multiple hallmarks of mitochondrial impairment: abnormal cristae and swollen mitochondria with increased average area, as observed with transmission electron microscopy, as well as reduced uncoupled oxygen consumption and decreased ATP levels
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La mayor parte de la evidencia publicada proviene de modelos animales (rata, ratn) y estudios in vitro

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