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35 BuretaC.SetoguchiT.SaitohY.TominagaH.MaedaS.NaganoS.et al (2019)

Abnormality of the a-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease

CH and YL reviewed the literature and contributed equally to the manuscript writing and editing

191 Further, with the exception of toxic metabolite production (Figure 3) that primarily affects liver function in adults but not babies, most physicians are largely unaware of the varied and complex effects of acetaminophen on the nervous system and on metabolism

This is consistent with the phase 2b clinical trial, where the total 12-week result was 2.8kg (6.2 lbs) additional fat loss versus placebo (clinical trial data)

Research indicates that the peptide might impact fibroblast communication, growth factor activity, and endothelial transitions