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The synthetic pathway encompasses numerous enzyme-mediated transformations, including a crucial reaction catalyzed by -butyrobetaine hydroxylase (-BBH)
Each hGM group was established by gavaging germ-free mice with 200 L of human fecal suspension, which was prepared by using a 1 g aliquot of feces diluted in 10 mL of reduced phosphate-buffered saline (supplemented with 0.05% l-cysteine) in an anaerobic chamber
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It is sometimes referred to as the 'tanning peptide' or 'Barbie drug' in popular media
