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Proc Natl Acad Sci USA (2009) 106:114005
doi: 10.1002/2211-5463.13351 196 SeoYJiYWLeeSMShimJNohHYeoAet al
The copper chelator, trientine (10 to 15 mg/kg PO q12h), is also effective for reducing hepatic copper concentrations
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Transmigrated PMNs in the lower chamber with reference beads were counted by flow cytometry (FACSCalibur
Even recent anti-amyloid immunotherapies, while targeting one of the core pathologies of AD, have shown limited clinical benefit and raised concerns regarding safety, efficacy, and applicability across the disease spectrum
