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Uncovering the Needs of Underserved Areas in Arequipa, Peru: Community Perspectives West Indian Medical Journal, 2016, 10.7727/wimj.2016.066 Goodrich DJ, Patel D, Loukas M, Tubbs RS, Oakes WJ

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Already in the 1940s, Charles Huggins and his colleagues demonstrated the effectiveness of ADT through surgical castration, which removes the major source of systemic androgen synthesis, as a treatment for advanced metastatic CaP [5, 6]