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Kwon DH, Cha HJ, Lee H, Hong SH, Park C, Park SH, Kim GY, Kim S, Kim HS, Hwang HJ, Choi YH

81, 173, 174 This said, only a few of these factors have been formally correlated with CDDP resistance in clinical studies, including various BCL-2-like proteins such as BCL-2 itself, BCL-X L and MCL-1, 175, 176, 177, 178 survivin, a caspase inhibitor that is often upregulated in response to CDDP, 179, 180, 181, 182 as well as other members of the baculoviral IAP repeat-containing (BIRC) protein family

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In conclusion, the experimental data are well described by the model for all knock-downs, except for slight deviations for siKEAP1, where the increase in Keap1-GFP and Srxn1-GFP after DEM exposure was underestimated by the model

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