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Description
Nat Rev Cancer 19(5):271282
NAD helps produce cellular energy, while glutathione protects the body from oxidative stress and toxins
Studies indicate that the lifetime risk of CRC in individuals with PMS2 mutations ranges between 10% and 20%, significantly lower than that of MLH1, MSH2, and MSH6 mutation carriers ( PMS2 carriers is estimated to be between 12% and 15%, also lower than those associated with other MMR genes
Enhanced Antioxidant Protection By neutralizing free radicals, glutathione protects cells from damage that can contribute to chronic diseases

A1_FPBT_2024_003
NAD kinase NADPH de novo synthesis is catalyzed by NADKs, which catalyze the phosphorylation of NAD + to form NADP +