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Abbreviations: C max , maximum serum concentration
TP53, encoded by the TP53 gene and mutated in over 50% of human cancers, is essential for cell-cycle regulation and the induction of programmed cell death
NDUFS6 knockout enhanced mitochondrial and intracellular reactive oxygen species (ROS) and reduced mitochondrial membrane potential
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Mounjaro is FDA-approved for adults with type 2 diabetes, while Zepbound is FDA-approved for chronic weight management in certain adults
Figure 5a,b)
