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They can get quite large

Individual outcomes vary significantly

These NAD+ deficits contribute to metabolic dysfunction by impairing insulin sensitivity, reducing mitochondrial function, and promoting inflammatory responses that exacerbate metabolic pathology in research models

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doi: 10.3389/fnbeh.2019.00123 188 OrtegaMAAlvarez-MonMAGarca-MonteroCFraile-MartinezOGuijarroLGLaheraGet al

& Goldstick, J
