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Anti-oxidant & antitoxin

Ligand binding triggers -secretase cleavage and nuclear translocation of the Notch intracellular domain (NICD), activating transcription factors Hairy and Enhancer of Split (Hes) and Hairy/Enhancer-of-split related with YRPW motif (Hey)

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Evidence of a systemic phenomenon for oxidative stress in cholestatic liver disease

It presents as a lingering bitter, tangy, or metallic flavor that doesnt go away with normal oral hygiene or eating

For those looking to dive deeper into the detox zone, take a look at our glutathione detoxification guide