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Evidence that human prostate cancer is a ZIP1-deficient malignancy that could be effectively treated with a zinc ionophore (Clioquinol) approach

Aucun effet systmique indsirable n'a t document lors de l'utilisation topique

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The Caughey and Prusiner labs had both discovered that PIPLC, an enzyme that can cleave GPI anchors, would release PrP C , but not proteinase K-resistant PrP Sc , from the surface of prion-infected cells, thus implying that whereas PrP C could be found on the cell surface, PrP Sc was buried somewhere inside the cell [Caughey 1990, Borchelt 1990, Taraboulos 1990]

Several clinical trials, including data published in The New England Journal of Medicine , have demonstrated that cagrilintide significantly reduces body weight in patients with obesity