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Zhao J, Wang L, Li Y, Zhao W, Kang S

Review 2.1

25 In Gram-negative bacteria, the loss or mutation of porin proteins restricts the entry of hydrophilic drugs

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Targeting microbial metabolic pathways may therefore provide a new entry point for understanding and treating FM (107)

The efficacy of MmDMSA in these animal models was seen through its effects on brain tissue, where it reduced ROS and restored the activity of SOD, GPx, GST and GSH after lead exposure