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Astrocytes are also involved in the recruitment of inflammatory cells to the site of injury, through the formation of a glial scar termed reactive astrogliosis which involves activation and proliferation of astrocytes to limit extending damage ( Bmal1 , shown through activation and increased inflammatory gene expression using an astrocyte specific Bmal1 knockout ( Bmal1 knockouts in astrocyte cultures have reported reduced actin-binding protein cortactin and impaired actin stress fiber formation ( Other immune cell populations that are involved in regulating the progression of ischemic injury are neutrophils, macrophages, and T-cells ( Bmal1 expression (Scheiermann et al., 2013)

Dihydroartemisinin: a potential natural anticancer drug

doi: 10.1093/jnen/64.2.113

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They have a male-to-female ratio of approximately 9:1