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Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response

doi: 10.1016/s0165-022x(01)00213-5

Notwithstanding the elevated clinical expectations that pertain to the development of drugs based on the modulation of the endocannabinoid system, setbacks are also present ( To better assess the interaction potential of existing or novel cannabinoids and other compounds affecting endocannabinoid system activity, it would be advisable to incorporate additional tests beyond the standard in vitro inhibition studies currently required by the EMA and FDA during preclinical drug evaluation

Abdomen was slightly distended, there was transverse operative scar in hypogastric area without bulging, neither in the umbilical nor inguinal region as seen in Fig