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Vitamin B3 (Niacin) Involved in energy metabolism, DNA repair, and cellular signaling, including pathways relevant to digestion and circulation

A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes

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For patients with pernicious anaemia or severe malabsorption , oral supplementation with either form is usually insufficient

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