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3 Role of immune cells in the pathogenesis of DKD 3.1 Macrophages Macrophages, which originate from circulating monocytes, are central innate immune cells that polarize into pro-inflammatory M1 or anti-inflammatory/pro-fibrotic M2 phenotypes in response to microenvironmental cues (50)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 159.Chang C.-H., Maren S
Valenzano A, Tartaglia N, Ambrosi A, et al
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