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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Konturek PC, Haziri D, Brzozowski T, Hess T, Heyman S, Kwiecien S, Konturek SJ, Koziel J

Patients who have taken substantial narcotic medications in the recent past may find that usual doses of pain medication are less effective

The result in phase 2 clinical trials was 24.2% mean body weight reduction at 48 weeks with the 12mg dose, and the first phase 3 TRIUMPH-4 trial reported an average of 28.7% weight loss at 68 weeks

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