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A multiplexed HILIC-MS/HRMS assay for the assessment of transporter Inhibition biomarkers in phase I clinical trials: Isobutyryl-Carnitine as an organic cation transporter (OCT1) biomarker

Front Physiol 5:402 Acknowledgements This work was supported by National Natural Science Foundation of China (to Q.L., Award Number 31771154, 31970933), Shanghai Brain-Intelligence Project from the Science and Technology Commission of Shanghai Municipality (18JC1420302), Shanghai Pujiang Program (to Q.L., Award Number 17PJ1405400), Program for Young Scholars of Special Appointment at Shanghai Institutions of Higher Learning (to Q.L., Award Number QD2018017), Innovative research team of high-level local universities in Shanghai, Fundamental Research Funds for the Central Universities (Shanghai Jiao Tong University, to Q.L., Award Number 17X100040037), the Project of Invigorating Health Care through Science, Technology and Education (ZDXKB2016015)

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doi:10.1089/jmf.2017.0068 Chaibi A, Tuchin PJ, Russell MB

Outcomes and other collected variables S-5-HT levels and behavioral fatigue levels had each been recorded twice, once before and once after the L-carnitine challenge