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MOTS-c MOTS-c is a mitochondrial-derived peptide thats often discussed in wellness and longevity communities for its potential role in metabolic flexibility and cellular energy support

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[2] [3] This may temporarily cause symptoms such as fatigue or headaches in some individuals

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He had compensatory increased GH, IGFBP-3, ALS as a result of lack of negative IGF-I feedback and secondary to the increased IGF binding capacity, increased IGF-II (see also the chapter on IGF-binding proteins below)