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These observations suggest that the degree of vessel normalization in terms of improved perfusion may be used as a tool to distinguish responders to anti-angiogenic therapy from non-responding patients [312, 313]

Molecular analysis showed that AP-treated rats were characterized by a decreased NF-B level, accompanied by a simultaneous reduction in HO-1 (heme oxygenase 1) expression compared to rats treated only with N -butyl- N -(4-hydroxybutyl)-nitrosamine

Factores como el estrs, la exposicin a contaminantes, la inflamacin o la sobrecarga metablica pueden incrementar la demanda antioxidante del organismo

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Changes in nuclear glutathione induced by DEM We studied the distribution of cellular GSH between cytoplasm and nucleus at different times of culture (6, 24, 48 and 72 hours)