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The metabolic acidosis results from the accumulation of plasma lactate and the ketone bodies, -hydroxybutyrate and acetoacetate

3.7 Mechanisms of action across probiotic genera The therapeutic efficacy of the diverse probiotic spectrum, spanning Bifidobacterium , Lactobacillus , spore-formers, and yeasts, is underpinned by a convergent yet distinct set of molecular mechanisms that maintain host homeostasis

Numerous physiological processes, such as inflammation, immunity, and detoxification, depend on it

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Cell Death In response to extra ROS accumulation, melanocytes undergo cell death in various ways including apoptosis, necrosis, autophagy, and ferroptosis [50]