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In conclusion, OA pathogenesis is propelled by a metabolically dysregulated milieu, where obesity, oxidative stress, gut dysbiosis, and broader metabolic syndrome converge to create a self-perpetuating cycle of inflammation and tissue damage (Figure 1)

Persistent malignant lymphadenopathy after preoperative chemoradiation identifies patients with poor postoperative survival

Modulation of Multiple Pathways Involved in the Maintenance of Neuronal Function During Aging by Fisetin. Genes & Nutrition 4: 297307
Moreover, in fresh samples from patients who underwent neoadjuvant chemotherapy, the GSH/GSSG levels in the resistant group were significantly higher than those in the sensitive group, which is consistent with previous research [28]

The small molecule compound Fer-1 inhibits the occurrence of ferroptosis, inhibits the overexpression of MT1G, and restores the migration and invasion functions of gastric cancer cells through iron autophagy induced by the GPX4/SQSTM1 axis (Fig
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