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These processes involve the activation of muscarinic cholinergic receptors in the forebrain, and an increased expression of type-2 metabotropic glutamate (mGlu2) receptors in dorsal root ganglia neurons

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Those with deficiency and insufficiency were then treated with 50,000 IU (1,250 mcg) of vitamin D per week for 12 weeks, resulting in improvements in measures of fibromyalgia severity and impact