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It is a combination of a GLP-1 agonist and an amylin agonist, explains Richard Siegel, MD, co-director of the Diabetes and Lipid Center at Tufts Medical Center and endocrinologist at Tufts Medicine Weight & Wellness Center Stoneham

The peptide is still in the early stages of animal studies

Deoxycholic acid activates colonic afferent nerves via 5-HT3 receptor-dependent and -independent mechanisms

This extended single dose toxicity study is the minimal requirement to perform Phase 0 clinical trials in humans

The goal is to deposit the peptide into subcutaneous fat, not muscle

We use fluoroscopic guidance to find the facet joint and inject the medication