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234,235,236,237 Unfortunately, tumor cells often remodel the tumor immune microenvironment through various mechanisms to achieve immune evasiveness, 238 such as reducing tumor antigen presentation, decreasing the infiltration or function of tumor-inhibitory immune cells, and promoting the infiltration of immunosuppressive cells

Kong et al., Research advances on the adverse effects of nanomaterials in a model organism

The polymer backbone covalently integrates an L-buthionine sulfoximine prodrug to inhibit glutathione biosynthesis, and the nanoparticle matrix encapsulates an elesclomol-copper complex to promote intratumoral copper accumulation

The products of these NRF2-regulated genes contribute to cellular defense mechanisms against OS and toxins [79]

It does this by donating an electron to stabilize the free radical , effectively neutralizing it and preventing it from reacting with other molecules in the cell

Gutierrez-MariscalFMArenas-de LarrivaAPLimia-PerezLRomero-CabreraJLYubero-SerranoEMLpez-MirandaJ