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Therefore, cancer cells not only use FAO to oxidize fatty acids and to derive energy by mitochondria but they also use acetyl-CoA to endogenously synthesize fatty acids in the cytosol using NADPH as key cofactor for anabolic enzymes (Koundouros and Poulogiannis, 2020)

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Wearne TA, Mirzaei M, Franklin JL, Goodchild AK, Haynes PA, Cornish JL

Zhao Q, Yang R, Wang J, Hu D-D, Li F

While our study does not establish causal molecular mechanisms, the coordinated improvement in oxidative stress biomarkers and NrF2/NF-B signaling is consistent with an overall attenuation of SRD-induced oxidative and inflammatory stress

T., Stephens, F