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Vitamin B12 is not the only consideration but it does play a big role in how you respond to MTHFR treatments

For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development

In children, decreased levels of intrinsic factor can be an inherited (genetic) condition

Those who eat less meat, have autoimmune or thyroid conditions are also more likely to experience anemia caused by vitamin B12 deficiency

Research suggests benefits for inflammatory bowel conditions, gastric ulcers, esophageal damage, and gut lining integrity

However, be mindful of portion sizes, as even healthy foods can contribute to weight gain if consumed in excess