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During cuproptosis, intracellular copper binds to the lipoylated components of the TCA cycle
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visualization V.S, M.P., G.B., V.S
[DOI] [PMC free article] [PubMed] [Google Scholar] 248.Reinhard K., Mnch T.A
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This oxidative damage is evidenced by elevated levels of 8-hydroxydeoxyguanosine, indicating compromised DNA integrity that facilitates mutations in melanoma-related genes like BRAF and loss of tumor-suppressor functions 119
